Bladder Cancer A Review Of The Environmental Risk Factors

Smoking causes about half of. The exact mechanism of bladder carcinogenesis in smokers remains unknown.


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There is ongoing research to identify and reduce risk factors as well as to understand the impact of genetics on bladder cancer risk.

Bladder cancer a review of the environmental risk factors. In addition to genetic factors a variety of environmental risk factors such as occupational exposure to chemical carcinogens cigarette smoking nutritional factors ingestion of analgesics or artificial sweeteners infection and inflammation radiation and chemotherapeutic agents can induce and promote the development and progression of bladder cancer. There is ongoing research to identify and reduce risk factors as well as to understand the impact of genetics on bladder cancer risk. The most notable risk factor for the development of bladder cancers is occupational exposure to aromatic amines 2-naphthylamine 4-aminobiphenyl and benzidine and 44-methylenebis 2-chloroaniline that can be found in the chemical dye and rubber industries as well as in hair dyes paints fungicides cigarette smoke plastics metal and motor vehicle exhaust.

Workplace exposures account for 5 to 25 of all bladder cancer cases. Common modifiable risk factors for bladder cancer include smoking history exposure to arsenic in high concentrations in drinking water occupational exposure aromatic amines hair dyes and. Smoking is the most important risk factor for bladder cancer.

The most notable risk factor for development of bladder cancer is occupational exposure to aromatic amines 2-naphthylamine 4-aminobiphenyl and benzidine and 44-methylenebis2-chloroaniline which can be found in the products of the chemical dye and rubber industries as well as in hair dyes paints fungicides cigarette smoke plastics metals and motor vehicle exhaust. Tobacco smoke is the most important exogenous risk factor for bladder cancer. The aim of this review is to investigate the links between various environmental risk factors and cancer of the bladderMethodsA systematic literature search was performed using PubMed Science Direct Scopus Scholar Google and Russian Google databases to identify reviews and epidemiological studies on bladder cancer risk factors associated with the environment published between 1998 and 2010.

Smoking is a well known risk factor of chronic lung disease heart disease and various types of cancer including bladder cancer 910Several epidemiological studies and reviews describe the impact of cigarette cigar pipe and environmental tobacco smoking. More than 60 carcinogens are present in tobacco smoke. Another factor strongly associated with bladder cancer.

Bladder cancer is common worldwide and the main risk factors are tobacco smoking and exposure to certain chemicals in the working and general envir-onments. Malignancies increases bladder cancer risk as does environmental contaminants such as arsenic. Smokers are at least 3times as likely to get bladder cancer as non-smokers.

Smoking is the most important risk factor for bladder cancer. Smokers are at least 3 times as likely to get bladder cancer as non-smokers. A critical review of the literature between 1938 and 2004 was performed with a focus on occupational exposures.

A systematic literature search was performed using PubMed Science Direct Scopus Scholar Google and Russian Google databases to identify reviews and epidemiological studies on bladder cancer risk factors associated with the environment published. Bladder cancer is common worldwide and the main risk factors are tobacco smoking and exposure to certain chemicals in the working and general environments. Smoking mainly cigarette smoking is a well known risk factor for various diseases including bladder cancer.

The aim of this review is to investigate the links between various environmental risk factors and cancer of the bladder. Russian Google databases to identify reviews and epidemiological studies on bladder cancer risk factors associated with the environment published between 1998 and 2010. Occupational exposure to bladder carcinogens particularly to beta-naphthylamine occur in a number of industries including aromatic amine manufacture rubber and cable manufacture and dyestuff manufacture and use.

Smokers are two to three times more likely to develop TCC and 50 of all bladder tumors are directly attributable to cigarette smoking. Smoking causes about half of. Bladder cancer a review of the environmental risk factors Silvia Letaiov 1 Albeta Medveov 1 Andrea ovkov 1 Mria Duinsk 2 4 Katarna Volkovov 2 Claudia Mosoiu 3 and Alena Bartonov 4.

Health care providers should ultimately seek to alleviate preventable disparities associated with increased risk of bladder cancer as well as be aware of less common high-risk patient populations. Only literature discussing human studies was considered.


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